Research and Reports
NitroPep's technology has been developed and patented by research teams at the University of Birmingham.
Independently-assessed laboratory data shows our covalently-bonded coating kills SARS-CoV-2, along with gram-negative and gram-positive bacteria and fungi.
Download some of the reports and research below.
NitroPep touch surface research and reports
There is an increasing focus in healthcare environments on combatting antimicrobial resistant infections. While bacterial infections are well reported, infections caused by fungi receive less attention, yet have a broad impact on society and can be deadly. In this study, a novel antimicrobial surface (AMS) that is modified with NitroPep's broad-spectrum biocide chlorhexidine is reported. The surfaces are shown to kill the opportunistic fungal pathogens Candida albicans and Cryptococcus neofor-mans very rapidly (<15 min) and are significantly more effective than current technologies available on the commercial market, such as silver and copper.
Read the report here.
In order to demonstrate that the NitroPep surface treatment can completely inactivate the SARS-CoV-2 virus we carried out a number of experiments on NitroPep treated metals, plastics and porous materials, to determine that the surfaces can inactivate the virus and completely sever the chain of transmission.
Download the full report here.
Testing was conducted on NitroPep coated 304 stainless steel for in-vitro cytotoxicity to ISO 10993-5 : 2009 and in-vitro irritation to ISO 10993-23 : 2021
The product passed the ISO test criteria.
Download the full report here.
Stainless steel surfaces treated with NitroPep were analysed for their antimicrobial activity against eMRSA 15, Pseudomonas aeruginosa and Candida albicans in the presence of a soiling agent compared to standard stainless steel.
Download the full report here.
Accelerated testing was carried out
independently of NitroPep by CPI. To simulate multiple touches on a surface over a 3 year period, surfaces underwent linear oscillating motion of a cloth covered stainless steel ball.
Download the full report here.
The biocidal efficacy of the NitroPep coated test stainless steel pieces was assessed against a set of uncoated control pieces using an inoculum of Escherichia Coli by Latis Scientific.
The average Log reduction across the test pieces was 2.81 when compared to the controls.
Download the full report here.
The biocidal efficacy of the NitroPep coated test pieces of ABS plastic was assessed against a set of uncoated control pieces using an inoculum of Escherichia Coli by Latis Scientific.
The average Log reduction across the test pieces was 2.81 when compared to the controls.
Download the full report here.
Both microbiology laboratory tests and trials in hospital settings of NitroPep's antimicrobial material (AMS) showed >99% efficacy over a year in situ. It maintains its efficacy through accelerated ageing tests and has shown to kill bacteria far more rapidly (45 min) than the commercially available technologies (24 h).
Read the report here.
NitroPep air filters research and reports
The COVID-19 pandemic has demonstrated the real need for mechanisms to control the spread of airborne respiratory pathogens. In this study we report on the efficacy of novel biocide treated filters and their antimicrobial activity against bacteria, fungi and viruses. The antimicrobial filters reported here are shown to kill pathogens, such as Candida albicans, Escherichia coli and MRSA in under 15 min and to destroy SARS-CoV-2 viral particles in under 30 s following contact with the filter.
Download the full report here.
NitroPep-treated air filters were installed at the Baltic Art Gallery in Gateshead, UK. The filters were then tested and compared to those without NitroPep treatment to determine the growth of microbial species.
NitroPep air filters showed excellent antimicrobial efficacy against all species and significantly reduced the microbial load in the system.
Download the full report here.
ToF SIMS was carried out on filters to determine the location of the NitroPep biocide.
Download the full report here.
We carried out a number of experiments on NitroPep treated metals, plastics and porous materials, to determine that the surfaces can inactivate SARS-CoV-2 and completely sever the chain of transmission.
In all experiments the NitroPep filters rapidly inactivated the SARS-CoV-2 virus as well as other pathogenic species. The data shows that the filter is capable of rapidly inactivating the virus in under 60 seconds giving a 6 log reduction in virus in under 60 seconds.
Download the full report here.
Download the full report here.
Microscopy of standard and NitroPep filters showed NitroPep treatment caused no structural changes.
Download the full report here.
Both standard and NitroPep treated filters were supplied to the testing laboratory. The filters had S. aureus applied to the surface and was then incubated at room temperature. The bacteria were extracted from the filter and cultured to determine the reduction in viability.
The data demonstrates that the NitroPep treated filter showed excellent efficacy against S. aureus with no culturable bacteria recovered from the filter.
Download the full report here.
Both standard and NitroPep treated filters were supplied to the testing laboratory. The filters had C. albicans applied to the surface and was then incubated at room temperature. The fungi were extracted from the filter and cultured to determine the reduction in viability.
The data demonstrates that the NitroPep treated filter showed excellent efficacy against C. albicans with no fungi recovered from the filter.
Download the full report here.